Last week, Dr. Quinton Smith, a Gerecht lab alumnus, and Dr. Sharon Gerecht’s recently published work on micropatterning human induced pluripotent stem cells to control cell cytoskeletal tension and regulate cell fate was featured on the HUB and Institute for NanoBioTechnology (INBT) websites! This work was performed in collaboration with Dr. Nash Rochman in Dr. Sean Sun’s lab at the Institute for NanoBioTechnology. The full article, entitled “Cytoskeletal Tension Regulates Mesodermal Spatial Organization and Subsequent Vascular Fate“, was published in the Proceedings of the National Academy of Sciences. To read the HUB or INBT articles and see Quinton’s beautiful images, visit the links below.
A sneak peak on how “machine learning unveils the roles of cell density (blue) and tension (red) on hiPSC self-organization in micropatterned shapes” is below! Photo credit: Quinton Smith and Sharon Gerecht